The meaning of 阴性 (yīnxìng) is deeply rooted in the philosophy of Yin and Yang (阴阳 - yīnyáng). In this worldview, Yin (阴) and Yang (阳) are not “good” vs. “evil” but are complementary, interdependent forces that govern the universe.
A key difference from Western thought is that a “negative” result is often positive news. If you are tested for a virus, a 阴性 result means you are clear, which is a very good thing! This contrasts with the Western tendency to associate the word “negative” with something bad. In the Chinese context, 阴性 in medicine simply means the absence or non-detection of something, a neutral state of being that is often the desired outcome. It reflects the value of balance; the absence of an invasive “Yang” element (like a virus) means the body is in its natural, balanced “Yin” state of health.
The overwhelming majority of modern usage for 阴性 is in clinical, medical, and scientific settings.
It is almost never used to describe a person's mood or attitude. For that, you would use words like 消极 (xiāojí) or 负面 (fùmiàn).