This chengyu is formal and carries a sense of gravity. It is used in situations where the potential negative outcome is significant.
Government and Public Policy: It is extremely common in government reports, official speeches, and public service announcements, especially concerning public health (e.g., pandemic control), environmental protection, and national security.
Business and Technology: In the corporate world, it's used to discuss risk management, cybersecurity, and quality control. A company might invest in robust server backups to 防患于未然.
Personal Life: While formal, it can be used for serious personal matters. For example, getting a comprehensive health check-up, starting a retirement fund early, or teaching a child about safety are all acts to 防患于未然.
Its connotation is always positive, praising a proactive and responsible approach.